آمار
| تعداد نشریات | 13 |
| تعداد شمارهها | 652 |
| تعداد مقالات | 6,807 |
| تعداد مشاهده مقاله | 9,609,087 |
| تعداد دریافت فایل اصل مقاله | 9,050,788 |
Effects of In Ovo Injection of Conjugated Linoleic Acid on Hatchability, Growth Performance, Intestine Morphology and Avian Β-Defensin Gene Expression in the Cecal Tonsils of Broiler Chicks | ||
| Poultry Science Journal | ||
| دوره 12، شماره 1، خرداد 2024، صفحه 75-85 اصل مقاله (1.1 M) | ||
| نوع مقاله: Original Paper | ||
| شناسه دیجیتال (DOI): 10.22069/psj.2023.20977.1894 | ||
| نویسندگان | ||
| Ahmad Hassanabadi* 1؛ Mona Azadeganmehr1؛ Seyed Ali Mirghelenj2 | ||
| 1Department of Animal Science, Faculty of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran | ||
| 2Department of Animal Science, Faculty of Agriculture, Urmia University, Urmia, Iran | ||
| چکیده | ||
| This experiment aimed to investigate the effects of in-ovo injection of conjugated linoleic acid (CLA) on growth performance and β-defensin (AvBD1 and AvBD2) genes expression in broilers. A total of 400 fertile eggs (Cobb 500) were randomly assigned to 4 treatments, each having five replicates of 20 eggs. CLA was injected into the air sack on 18 d of incubation (150 and 300 mg/egg; CLA150 and CLA300). Two groups of diluent injected and non-injected were also included as controls. Hatchlings were further evaluated in a 42-d rearing period. Data were analyzed using a completely randomized design. Results showed that the hatchability was not significantly affected by the treatments. The growth performance in the CLA300 group was improved (P < 0.05) compared to both controls. CLA300 increased (P < 0.05) the jejunal villus length on 42 d, leading to a significant increase in villus absorptive surface area (P < 0.05) compared to CLA150 or controls. Abdominal fat weight in the CLA300 group was significantly decreased on 42 d (P < 0.05). The expression of β-defensins was detectable in all groups on 21 and 42 d, irrespective of treatment and age. Differences in AvBD1 gene expression in chicks from different treatments were not significant on 21 d, but the expression level in CLA received groups was more than controls at 42 d (P < 0.05). AvBD2 gene expression in CLA-treated birds was increased compared to controls on 21 d, but only the CLA300 group showed a significant increase compared to both controls on 42 d (P < 0.05). Research highlights: in ovo feeding 300 mg CLA per egg into the air sac decreased abdominal fat pad, improved growth performance and villous absorptive surface area of the jejunum and increased AvBD1 and AvBD2 gene expression in broilers. | ||
| کلیدواژهها | ||
| Broiler؛ In ovo feeding؛ Intestinal morphology؛ Performance؛ β-defensins | ||
| مراجع | ||
|
Alipour M, Navidshad B, Adib Moradi M & Seyed Sharifi R. 2010. Effect of conjugated linoleic acid on performance and small intestine morphology of broiler chickens. Research on Animal Production (Scientific and Research), 1: 22-36.
Almamury A, Hassanabadi A, Zerehdaran S & Nassiri-Moghaddam H. 2022. Supplementing a herbal product (NBS Superfood) in broiler diets varying in energy and protein levels: effects on growth performance, intestinal morphology, immune response and blood metabolites. Poultry Science Journal, 10: 59-70. DOI: 10.22069/psj.2022.19535.1734
Amer SA, Beheiry RR, Abdel Fattah DM, Roushdy EM, Hassan FA, Ismail TA, Zaitoun NM, Abo-Elmaaty AM & Metwally AE. 2021. Effects of different feeding regimens with protease supplementation on growth, amino acid digestibility, economic efficiency, blood biochemical parameters, and intestinal histology in broiler chickens. BMC Veterinary Research, 17: 1-6. DOI: 10.1186/s12917-021-02946-2
Asare E, Yang Z, Yang H & Wang Z. 2022. Evaluation of dietary Pancreatin as an exogenous enzyme on growth performance, gene expression, immunological responses, serum immunoglobins, and intestinal morphology in cockerels. Journal of Applied Animal Research, 50: 61-68. DOI: 10.1080/09712119.2021.201904
Azadegan mehr M, Hassanabadi A, Mirghelenj SA & Kermanshasi H. 2014. Effect of in ovo injection of conjugated linoleic acid on immune status and blood biochemical factors of broilers chickens. Spanish Journal of Agricultural Research, 12: 455–461. DOI: 10.5424/sjar/2014122-4901
Badinga L, Selberg KT, Dinges AC, Comer CW & Miles RD. 2003. Dietary conjugated linoleic acid alters hepatic lipid content and fatty acid composition in broiler chickens. Poultry Science, 82: 111–116. DOI: 10.1093/ps/82.1.111
Bommineni YR, Dai H, Gong YX, Soulages JL, Fernando SC, DeSilva U, Prakash O & Zhang G. 2007. Fowlicidin‐3 is an α‐helical cationic host defense peptide with potent antibacterial and lipopolysaccharide‐neutralizing activities. The FEBS Journal, 274: 418-428. DOI: 10.1111/j.1742-4658.2006.05589.x
Choi YH. 2009. Conjugated linoleic acid as a key regulator of performance, lipid metabolism, development, stress and immune functions, and gene expression in chickens. Asian-Australasian Journal of Animal Sciences, 22: 448-458. DOI: 10.5713/ajas.2009.r.04
Du M & Ahn DU. 2002. Effect of dietary conjugated linoleic acid on the growth rate of live birds and on the abdominal fat content and quality of broiler meat. Poultry science, 81: 428-433. DOI: 10.1093/ps/81.3.428
Du M, Ahn DU, Nam KC & Sell JL. 2001. Volatile profiles and lipid oxidation of irradiated raw chicken meat patties from laying hens fed with diets containing conjugated linoleic acid. Poultry Science, 80: 235–241. DOI: 10.1093/ps/80.2.235
Fazli N, Hassanabadi A, Mottaghitalab M & Hajati H. 2015. Manipulation of broiler chickens sex differentiation by in ovo injection of aromatase inhibitors, and garlic and tomato extracts. Poultry science, 94: 2778-2783. DOI: 0.3382/ps/pev236
Fu C, Zhang Y, Wang W, Wei X, Yan P, Shi T & Liu X. 2021. Supplementing conjugated linoleic acid (CLA) in breeder hens diet increased CLA incorporation in liver and alters hepatic lipid metabolism in chick offspring. British Journal of Nutrition, 2021: 1-41. DOI: 10.1017/S0007114521000763
Fu C, Zhang Y, Yao Q, Wei X, Shi T, Yan P & Liu X. 2020. Maternal conjugated linoleic acid alters hepatic lipid metabolism via the AMPK signaling pathway in chick embryos. Poultry Science, 99: 224-234. DOI: 10.3382/ps/pez462
Ganz T. 2003. Defensins: Antimicrobial peptides of innate immunity. Nature, 3: 710–720. DOI: 10.1016/j.crvi.2003.12.007
Guo M, Liu D, Chen X, Wu Y, & Zhang X. 2022. Pathogenicity and innate response to Avibacterium paragallinarum in chickens. Poultry Science, 101: 101523. DOI: 10.1016/j.psj.2021.101523
Higgs R, Lynn DJ, Gaines S, McMahon J, Tierney J, James T, Lloyd AT, Mulcahy G & O’Farrelly C. 2005. The synthetic form of a novel chicken β-defensin identified in silico is predominantly active against intestinal pathogens. Immunogenetics, 57: 90-98. DOI: 10.1007/s00251-005-0777-3
Jiang W, Nie S, Qu Z, Bi C, Shan A. 2014. The effects of conjugated linoleic acid on growth performance, carcass traits, meat quality, antioxidant capacity, and fatty acid composition of broilers fed corn dried distillers grains with solubles. Poultry Science, 93: 1202-1210. DOI: 10.3382/ps.2013-03683
Kakhki RA, Bakhshalinejad R, Hassanabadi A & Ferket P. 2017. Effects of dietary organic zinc and α-tocopheryl acetate supplements on growth performance, meat quality, tissues minerals, and α-tocopherol deposition in broiler chickens. Poultry Science, 96: 1257-1267. DOI: 10.3382/ps/pew386
Kumari S, Yong Meng G & Ebrahimi M. 2017. Conjugated linoleic acid as functional food in poultry products: A review. International Journal of Food Properties, 20: 491-506. DOI: 10.1080/10942912.2016.1168835
Leão AP, Alvarenga RR & Zangeronimo MG. 2021. In ovo inoculation of probiotics for broiler chickens: systematic review and meta-analysis. Animal Feed Science and Technology, 280:115080. DOI: 10.1016/j.anifeedsci.2021.115080
Lynn DJ, Higgs R, Gaines S, Tierney J, James T, Lloyd AT, Fares MA, Mulcahy G & O’Farrelly C. 2004. Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken. Immunogenetics, 56: 170-177. DOI: 10.1007/s00251-004-0675-0
Lynn DJ, Higgs R, Lloyd AT, O'Farrelly C, Hervé-Grépinet V, Nys Y, Brinkman FS, Yu PL, Soulier A, Kaiser P & Zhang G. 2007. Avian beta-defensin nomenclature: a community proposed update. Immunology letters, 110: 86-89. DOI: 10.1016/j.imlet.2007.03.007
Martin D, Muriel E, Gonzalez E, Viguera J & Ruiz J. 2008. Effect of dietary conjugated linoleic acid and monounsaturated fatty acids on productive, carcass and meat quality traits of pigs. Livestock Science, 117: 155–164. DOI: 10.1016/j.livsci.2007.12.005
Menendez A & Finlay BB. 2007. Defensins in the immunology of bacterial infections. Current Opinion in Immunology, 19: 385-391. DOI: 10.1016/j.coi.2007.06.008
Milona P, Townes CL, Bevan RM & Hall J. 2007. The chicken host peptides, gallinacins 4, 7, and 9 have antimicrobial activity against Salmonella serovars. Biochemical and Biophysical Research Communications, 356: 169-174. DOI: 10.1016/j.bbrc.2007.02.098
Moran Jr ET. 2007. Nutrition of the developing embryo and hatchling. Poultry science, 86: 1043-1049. DOI: 10.1093/ps/86.5.1043
Muma E, Palander S, Näsi M, Pfeiffer AM, Keller T & Griinari JM. 2006. Modulation of conjugated linoleic acid-induced loss of chicken egg hatchability by dietary soybean oil. Poultry Science, 85: 712-720. DOI: 10.1093/ps/85.4.712
Rodríguez-Lecompte JC, Yitbarek A, Brady J, Sharif S, Cavanagh MD, Crow G, Guenter W, House JD & Camelo-Jaimes G. 2012. The effect of microbial-nutrient interaction on the immune system of young chicks after early probiotic and organic acid administration. Journal of Animal Science, 90: 2246-2254. DOI: 10.2527/jas.2011-4184
Sahl HG, Pag U, Bonness S, Wagner S, Antcheva N & Tossi A. 2005. Mammalian defensins: structures and mechanism of antibiotic activity. Journal of Leukocyte Biology, 77: 466-475. DOI: 10.1189/jlb.0804452
SAS (Statistical Analyses System). 2012. SAS/STAT Software, Version 9.4. Cary (NC): SAS Institute Inc.
Schlee M, Harder J, Köten B, Stange EF, Wehkamp J & Fellermann K. 2008. Probiotic lactobacilli and VSL# 3 induce enterocyte β-defensin 2. Clinical & Experimental Immunology, 151: 528-535. DOI: 10.1111/j.1365-2249.2007.03587.x
Sirri F, Tallarico N, Meluzzi A & Franchini A. 2003. Fatty acid composition and productive traits of broiler fed diets containing conjugated linoleic acid. Poultry Science, 82: 1356–1361. DOI: 10.1093/ps/82.8.1356
Stangl GI. 2000. High dietary levels of a conjugated linoleic acid mixture alter hepatic glycerophospholipid class profile and cholesterol-carrying serum lipoproteins of rats. The Journal of Nutritional Biochemistry, 11: 184-191. DOI: 10.1016/S0955-2863(00)00063-2
Subedi K, Isobe N, Nishibori M & Yoshimura Y. 2007. Changes in the expression of gallinacins, antimicrobial peptides, in ovarian follicles during follicular growth and in response to lipopolysaccharide in laying hens (Gallus domesticus). Reproduction, 133: 127-133. DOI: 10.1530/REP-06-0083
Sugiarto H & Yu PL. 2004. Avian antimicrobial peptides: the defense role of β-defensins. Biochemical and biophysical research communications, 323:721-727. DOI: 10.1016/j.bbrc.2004.08.162
Suksombat W, Boonmee T & Lounglawan P. 2007. Effects of various levels of conjugated linoleic acid supplementation on fatty acid content and carcass composition of broilers. Poultry Science, 86: 318-324. DOI: 10.1093/ps/86.2.318
Takahashi K, Kawamata K, Akiba Y, Iwata T & Kasai M. 2002. Influence of dietary conjugated linoleic acid isomers on early inflammatory responses in male broiler chickens. British Poultry Science, 43: 47-53. DOI: 10.1080/00071660120109881
Tan J, Wan L, Chen X, Li X, Hao X, Li X, Li J & Ding H. 2019. Conjugated linoleic acid ameliorates high fructose‐induced hyperuricemia and renal inflammation in rats via NLRP3 inflammasome and TLR4 signaling pathway. Molecular nutrition & food research, 63: 1801402. DOI: 10.1002/mnfr.201801402
Uni Z & Ferket PR. 2003. Enhancement of development of oviparous species by in ovo feeding patent 6, 592, 878. Notrh Caroline state University, Raleigh, NG.
van Dijk A, Veldhuizen EJ, Kalkhove SI, Tjeerdsma-van Bokhoven JL, Romijn RA & Haagsman HP. 2007. The β-defensin gallinacin-6 is expressed in the chicken digestive tract and has antimicrobial activity against food-borne pathogens. Antimicrobial Agents and Chemotherapy, 51: 912-922. DOI: 10.1128/AAC.00568-06
Wang G, Kim WK, Cline MA & Gilbert ER. 2017. Factors affecting adipose tissue development in chickens: A review. Poultry Science, 96: 3687-3699. DOI: 10.3382/ps/pex184
Yoshimura Y, Ohashi H, Subedi K, Nishibori M & Isobe N. 2006. Effects of age, egg-laying activity, and Salmonella-inoculation on the expressions of gallinacin mRNA in the vagina of the hen oviduct. Journal of Reproduction and Development, 52: 211-218. | ||
|
آمار تعداد مشاهده مقاله: 420 تعداد دریافت فایل اصل مقاله: 421 |
||
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب