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Effects of Milk Thistle, Artichoke and Olive Extracts in Comparison with Atorvastatin and Gemfibrozil on Liver Function in Broiler Chicken | ||
| Poultry Science Journal | ||
| مقاله 12، دوره 8، شماره 1، مرداد 2020، صفحه 109-117 اصل مقاله (471.02 K) | ||
| نوع مقاله: Original Paper | ||
| شناسه دیجیتال (DOI): 10.22069/psj.2020.17689.1545 | ||
| نویسندگان | ||
| F Tavakolinasab؛ H Khosravinia* ؛ B Masouri | ||
| Department of Animal Sciences, Agriculture Faculty, Lorestan University, Khorramabad, Iran | ||
| چکیده | ||
| One hundred forty four 10-day old male Arbor Acres (320±5g) broiler chicks were used to compare the responses in liver function to dietary supplementation of milk thistle (Silybum marianum), artichoke (Cichorium intybus) and olive (Olea europaea) extracts with gemfibrozil and atorvastatin, in broiler chickens fed with a lipogenic diet. Birds raised in the standard experimental conditions and received a pelleted grower diet (control) supplemented with milk thistle (250 mg/kg), artichoke (200 mg/kg), olive (150 mg/kg) extracts, atorvastatin (20 mg/kg) and gemfibrozil (1800 mg/kg) up to day 42 of age. Liver weight and liver fat parentages were 1.62 and 6.04%, respectively, in the birds fed with the un-supplemented basal diet (control) and modified by +0.21 and -2.13, +0.11 and -1.21, +0.14 and -1.40, -0.07 and -2.36, +0.07 and -0.38% in the birds received milk thistle, artichoke, olive extracts, gemfibrozil, and atorvastatin, respectively. The milk thistle-added diet elicited a significant reduction in serum activity of aspartate aminotransferase and alanine aminotransferase at day 35 of age. Dietary olive extract at 150 mg/kg reduced liver fat at day 35 of age compared with those grown on the basal diet (P < 0.05). The serum concentration of triglycerides was lower (P < 0.05) in the birds fed with diets enriched with artichoke (34.86 mg/dL) and olive extract (40.63 mg/dL) compared with those fed with the supplemented control diet at day 35 of age. It was concluded that milk thistle exerted greater promising hepatoprotective effects compared with other remedies. Gemfibrozil exhibited a greater hepatoprotective and blood lipid-lowering effect than atorvastatin in broiler chicken. | ||
| کلیدواژهها | ||
| Atorvastatin؛ Gemfibrozil؛ Broiler chicken؛ Herbal medicine؛ Hepatoprotection | ||
| مراجع | ||
|
Alshamy Z, Richardson KC, Harash G, Hünigen H, Röhe I, Hafez HM, Johanna P & Salah A. 2019. Structure and age-dependent growth of the chicken liver together with liver fat quantification: A comparison between a dual-purpose and a broiler chicken line. PLoS ONE, 14: e0226903. DOI: 10.1371/journal.pone.0226903
Alvin Jose M, Anandkumar S, Narmadha MP & Sandeep MA. 2012. Comparative effect of atorvastatin with other statins in patients of hyperlipidemia. Indian Pharmacology, 44: 261–263. DOI: 10.4103/0253-7613.93864
Andrikopoulos NK, Antonopoulou S & Kaliora AC. 2002. Oleuropein inhibits LDL oxidation induced by cooking oil frying by-products and platelet aggregation induced by platelet-activating factor. LWT. Food’s Science and Technology, 35: 479-484. DOI: 10.1006/fstl.2002.0893
Arslan C, Citil M & Saatci M. 2003. Effects of L-carnitine administration on growth performance, carcass traits, blood serum parameters and abdominal fatty acid composition of ducks. Archiv fur Tierzucht, 57: 381-88. DOI: 10.1080/00039420310001607734
Ayala I, Martin Castillo A, Adanez G, Fernandez-Rufete A, Garci´Aperez B & Castells MT. 2009. Hyperlipidemic Chicken as a Model of Non-Alcoholic Steatohepatitis. Experimenatl Biological Mededicine, 234: 10-16. DOI: 10.3181/0807-RM-219
Azcona J, Schang M & Mallo G. 2005. Effect on the zootechnical response of broilers of the inclusion of artichoke extract (Cynara scolymus L.) in the diet]. Reports of the XIXth Latin American Congress on Poultry Farming, Panamá.
Cherian G, Holsonbake T, Goeger M & Bildfell R. 2002. Dietary CLA alters yolk and tissue FA composition and hepatic histopathology of laying hens. Lipids, 37: 751–757. DOI: 10.1007/s11745-002-0957-4
Corey KE & Chalasani N. 2014. Management of Dyslipidemia as a Cardiovascular Risk Factor in Individuals With Nonalcoholic Fatty Liver Disease. Clinical Gastroenterology Hepatology, 12: 1077–1084. DOI: 10.1016/j.cgh.2013.08.014
Farrokhyan P, Bouyeh M, Lartey FM & Seidavi A. 2014. The effects of dietary L-carnitine and gemfibrozil on performance, carcass characteristics, cholesterol and triglycerides in broiler chicks. Avian Biology Research,7: 160-166. DOI: 10.3184/175815514X14067215301247
Ferramosca A, Di Giacomo M & Zara V. 2017. Antioxidant dietary approach in treatment of fatty liver: New insights and updates. Worlds Journal of Gastroenterology, 23: 4146–4157. DOI: 10.3748/wjg.v23.i23.4146
Folch J, Lees MG & Stanley HS. 1956. A simple method for the isolation and purification of total lipids from animal tissues. Journal of Biological Chemistry, 226: 497-509.
Gawel A, Kotonski B, Madej JA & Mazurkiewicz M. 2003. Effect of silymarin on chicken and turkey broilers’ rearing and the production indices of reproduction hen flocks. Medycyna Weterynaryjna, 59: 517–520.
Gebhardt R. 2002. Inhibition of cholesterol biosynthesis in HepG2 cells by artichoke extracts is reinforced by glucosidase pretreatment. Phytotherapy Research,16: 368-72. DOI: 10.1002/ptr.960
Hillgartner FB, Salati LM & Goodridge AG. 1995. Physiological and molecular mechanisms involved in nutritional regulation of fatty acid synthesis. Physiology Research, 75: 47-76. DOI: 10.1152/physrev.1995.75.1.47
Jafari Golrokh A, Bouyeh M, Seidavi A, van den Hoven R, Laudadio V & Tufarelli V. 2016. Effect of different dietary levels of atorvastatin and L-carnitine on performance, carcass characteristics and plasma constitutes of broiler chickens. The Journal of Poultry Science, 53: 201-207. DOI: 10.2141/jpsa.0150184
Khosravinia H, Chethen PS, Ukmakantha B & Nourmohamadi R. 2015. Effects of lipotropic products on productive performance, liver lipid and enzymes activity in broiler chickens. Poultry Science, 3: 113-120. DOI: 10.22069/PSJ.2015.2648
Kolovou GD, Mikhailidis DP, Kafaltis N, Adamopoulou EN, Yazitsoglou E & Hatzaki A. 2004. The Effect of Alcohol and Gemfibrozil Co-administration in Wistar Rats. In Vivo,18: 49-54.
Kramer CY. 1956. Extension of multiple range tests to group means with unequal number of replications. Biometery,12: 307-310. DOI: 10.2307/3001469
Krzeminski R, Gorinstein S, Leontowicz H, Leontowicz M, Gralak M & Czerwinski J. 2003. Effect of different olive oils on bile excretion in rats fed cholesterol-containing and cholesterol-free diets. AgricultureFood Chemistry51: 5774– 5779. DOI: 10.1021/jf030088a
Kulkarni YA, Yele VU, Addepalli V & Kulkarni KS. 2012. Nonalcoholic fatty liver diseases: Introspection. Pharmacology on Line,3: 104-112.
Kwon DY, Jung YS, Kim S.J, Kim YS, Choi DW & Kim YC. 2013. Alterations in sulfur amino acid metabolism in mice treated with silymarin: a novel mechanism of its action involved in enhancement of the antioxidant defense in liver. Planta Medicine, 79: 997-1002. DOI: 10.1055/s-0032-1328704
Makovick P, Dudova M, Tumova E, Rajmon R & Vodkova Z. 2011. Experimental study of non-alcoholic fatty liver disease (NAFLD) on a model of starving chickens: is generalization of steatosis accompanied by fibrosis of the liver tissue? Pathological Research Practice, 15: 207: 151-155. DOI: 10.1016/j.prp.2010.12.002
Metwally MAA, El-Gellal AM & El-Sawaisi SM. 2009. Effects of Silymarin on Lipid Metabolism in Rats. World Applied Science,6: 1634-1637
Nagashima S, Yagyu H, Ohashi K, Tazoe F, Takahashi M & Ohshiro T. 2012. Liver-specific deletion of 3-hydroxy-3-methylglutaryl coenzyme A reductase causes hepatic steatosis and death. ArteriosclerosisThrombosis Vascular Biology, 32: 1824–1831. DOI: 10.1161/ATVBAHA.111.240754
Önel SE, Sungur S & Baylan M. 2017. Effects of supplementary choline on quail meat and fatty liver. Brazilian Journal of Animal Sciences, 46: 645-651. DOI: 10.1590/s1806-92902017000800003
Pastori D, Polimeni L, Baratta F, Pani A, Del Ben M & Angelico, F. 2015. The efficacy and safety of statins for the treatment of non-alcoholic fatty liver disease. Digestive Liver Diseases, 47: 4-11. DOI: 10.1016/j.dld.2014.07.170
Qiang Z, Lee SO, Ye Z, Wu X & Hendrich S. 2012. Artichoke extract lowered plasma cholesterol and increased fecal bile acids in Golden Syrian hamsters. Phytotherapy Research, 26: 1048-1052. DOI: 10.1002/ptr.3698
Statistical Analysis System. 2003. SAS Users Guide: Statistics. Ver. 6. Cary, NC.
Tang X, Wei R, Deng A & Lei T. 2017. Protective Effects of Ethanolic Extracts from Artichoke, an Edible Herbal Medicine, against Acute Alcohol-Induced Liver Injury in Mice. Nuts9: 1000. DOI: 10.3390/nu.9091000
Trott KA, Giannitti F, Rimoldi G, Hill A, Woods L & Barr B. 2014. Fatty Liver Hemorrhagic Syndrome in the Backyard Chicken, A Retrospective Histopathologic Case Series. Veterinary Pathology, 51: 787-795. DOI: 10.1177/0300985813503569
Tufarelli V, Laudadio V & Casalino E. 2016. An extra-virgin olive oil rich in polyphenolic compounds has antioxidant effects in meat-type broiler chickens. Environmental Science and Pollution Research, 23: 6197-6204. DOI: 10.1007/s11356-015-5852-1
Wani FA, Albahrawy ZA & Shaik Rahiman, S. 2015. Hypolipidemic Activity of Olive Oil (Olea europaea) against High Fat Diet-Induced Nonalcoholic Fatty Liver Disease (NAFLD) in Mice. PLoS One, 5: 73-83. DOI: 10.4236/ojpathology.2015.53011
Xiao J, Guo R, Fung ML, Liong EC & Tipoe GL. 2013. Therapeutic Approaches to Non-Alcoholic Fatty Liver Disease: Past Achievements and Future Challenges. Hepatobiliary & Pancreatic Diseases International, 12: 125-135. DOI: 10.1016/S1499-3872 (13)60021-1
Xiao Quan G, HuaBin C, GuoLiang H, CaiYing Z, HaoTang L & HongFeng C. 2012. Effect of a high-energy low-protein diet supplemented with biotin on fat metabolism of laying hen. China Journal of Veterinary Sciences, 32: 754–758. DOI: 10.3382/ps /pev367 | ||
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