آمار
| تعداد نشریات | 13 |
| تعداد شمارهها | 642 |
| تعداد مقالات | 6,700 |
| تعداد مشاهده مقاله | 9,213,833 |
| تعداد دریافت فایل اصل مقاله | 8,640,937 |
Effects of Probiotic and/or Prebiotic Supplementations on Immune Response, Haematology, Oxidant-antioxidant Biomarkers, and Cytokine mRNA Expression Levels in the Caeca of Broilers Infected with Salmonella | ||
| Poultry Science Journal | ||
| دوره 9، شماره 1، شهریور 2021، صفحه 41-52 اصل مقاله (381.53 K) | ||
| نوع مقاله: Original Paper | ||
| شناسه دیجیتال (DOI): 10.22069/psj.2021.18438.1637 | ||
| نویسندگان | ||
| R Tarabees1؛ HM Hafez2؛ AA Shehata3؛ TS Allam* 4؛ A Setta5؛ MSA ELsayed6 | ||
| 11Department of Bacteriology, Mycology, and Immunology, Faculty of Veterinary Medicine, University of Sadat City, Sadat City, Egypt | ||
| 2Institute of Poultry Diseases, Free University Berlin königsweg 63, 14163 Berlin, Germany | ||
| 33Department of Birds and Rabbit Diseases, Faculty of Veterinary Medicine, University of Sadat City, Sadat City, Egypt | ||
| 4Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Sadat City, Sadat City, Egypt | ||
| 5Department of Poultry Diseases, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt | ||
| 6Department of Bacteriology, Mycology, and Immunology, Faculty of Veterinary Medicine, University of Sadat City, Sadat City, Egypt | ||
| چکیده | ||
| The present study was conducted to evaluate the effects of incorporation of the probiotic mix, prebiotic, and synbiotic supplements on immune response, interleukin-6, interleukin-10, and inducible nitric oxide synthase (iNOS) gene expression, hematology, and oxidant-antioxidant biomarkers of broilers infected with Salmonella Enteritidis and Salmonella Typhimurium mixed infection. A total of 273 commercial Cobb 500 chicks were randomly allocated into seven experimental groups, including NC group: fed only a basal diet (negative control), PC group; fed a basal diet and infected with Salmonellae on 3rd life day (positive control), ProSa group: administrated probiotic mix in drinking water and then infected with Salmonellae, Presa group: fed prebiotic with basal diet and then infected with Salmonellae, SynSa: received probiotic mix and prebiotic (synbiotic) and then infected with Salmonellae, Pro group: given probiotic mix in feed, and Pre group: basal diet supplemented with prebiotic. The probiotic mix, prebiotic, and synbiotic supplementation significantly increased total IgY levels in the sera of infected birds in comparison to those of positive control. Also, the additives significantly down regulated IL-6 and iNOS gene expressions while they significantly up regulated IL-10 gene expression in the caeca of infected birds, in comparison to those of positive control. Also, the supplementary treatments significantly improved Salmonella induced changes in hematology and oxidant antioxidant biomarkers of infected groups. Compared with different supplementary treatments, the synbiotic significantly robust immune response of Salmonella infected birds when compared with single supplementation of probiotic mix or prebiotic. In conclusion, probiotics, prebiotic, and in particular synbiotic supplements improved immune response, hematological and antioxidative biomarkers of birds experimentally infected with mixed Salmonellae. | ||
| کلیدواژهها | ||
| Broiler؛ Prebiotic؛ Salmonella؛ Probiotic mix؛ Immune response | ||
| مراجع | ||
|
Abdel-Latif MA, El-Hack A, Mohamed E, Swelum AA, Saadeldin IM, Elbestawy AR & El-Hamid A. 2018. Single and combined effects of Clostridium butyricum and Saccharomyces cerevisiae on growth indices, intestinal health, and immunity of broilers. Animals, 8: 184. DOI: 10.3390/ani8100184.
Awotwi EK & Boohene YG. 1992. Hematological studies on some poultry species in Ghana. Bulletin of Animal Production in Africa, 40: 65–71.
Beutler E, Duron O & Kerlly B. 1963. Improved method for the determination of blood glutathione. Journal of Laboratory Clinical Medicine, 61: 882–888.
Chappell L, Kaiser P, Barrow P, Jones MA, Johnston C & Wigley P. 2009. The immunobiology of avian systemic salmonellosis. Veterinary Immunology and Immunopathology, 128: 53–59. DOI: 10.1016/j.vetimm.2008.10.295
Chauhan HVS & Verma KC. 1983. Evaluation of Cell-Mediated Immunity to Marek’s Disease. British Veterinary Journal, 139: 6–14. DOI: 10.1016/S0007-1935(17)30582-1
Chen CY, Tsen HY, Lin CL, Lin CK, Chuang LT, Chen CS & Chiang YC. 2013. Enhancement of the immune response against Salmonella infection of mice by heat-killed multispecies combinations of lactic acid bacteria. Journal of Medical Microbiology, 62: 1657–1664. DOI: 10.1099/ jmm.0.061010-0
Christensen HR, Frøkiær H, Pestka JJ.. 2002. Lactobacilli differentially modulate expression of cytokines and maturation surface markers in murine dendritic cells. Journal of Immunology (Baltimore, Md. : 1950), 168: 171–178. DOI: 10.4049/jimmunol.168.1.171
Feldman BF, Zinkl JC & jain NC. 2000." Schalm’s Veterinary Hematology", 5th. Lippincott Williams & Wilkins, Philadelphia, London.
Forkus B, Ritter S, Vlysidis M, Geldart K & Kaznessis YN. 2017. Antimicrobial probiotics reduce Salmonella enterica in turkey gastrointestinal tracts. Scientific Reports, 7: 1–9. DOI: 10.1038/srep40695
Gadde UD, Oh S, Lee Y, Davis E, Zimmerman N, Rehberger T & Lillehoj HS. 2017. Dietary Bacillus subtilis-based direct-fed microbials alleviate LPS-induced intestinal immunological stress and improve intestinal barrier gene expression in commercial broiler chickens. Research in Veterinary Science, 114: 236–243. DOI: 10.1016/j.rvsc.2017.05.004
Ghenioa AM, Ashry KM & Nazem AM. 2015. Protective Effect of Probiotic Bactosac® Against Induced Sub Chronic Lead Toxicity in Broiler Chicks. Alexandria Journal of Veterinary Sciences, 47. DOI: 10.5455/ajvs.200070
Haghighi HR, Abdul-Careem MF, Dara RA, Chambers JR & Sharif S. 2008. Cytokine gene expression in chicken cecal tonsils following treatment with probiotics and Salmonella infection. Veterinary Microbiology, 126: 225–233. DOI: 10.1016/j.vetmic.2007.06.026
Ilstrup DM. 1990. Statistical methods in microbiology. Clinical Microbiology Reviews, 3: 219–226. DOI: 10.1128/CMR.3.3.219
Kaiser P, Rothwell L, Galyov EE, Barrow PA, Burnside J & Wigley P. 2000. Differential cytokine expression in avian cells in response to invasion by Salmonella Typhimurium, Salmonella Enteritidis and Salmonella Gallinarum. Microbiology, 146: 3217-3226. DOI: 10.1099/00 221287-146-12-3217
Knap I, Kehlet AB, Bennedsen M, Mathis GF, Hofacre CL, Lumpkins BS & Lay A. 2011. Bacillus subtilis (DSM17299) significantly reduces Salmonella in broilers. Poultry Science, 90: 1690–1694. DOI: 10.3382/ps.2010-01056
Koenen ME, Kramer J, Van Der Hulst R, Heres L, Jeurissen SHM & Boersma WJA. 2004. Immunomodulation by probiotic lactobacilli in layer-and meat-type chickens. British Poultry Science, 45: 355–366. DOI: 10.1080/ 000716604 10001730851
Kokosharov T. 2002. Clinical and hematological effects of Salmonella gallinarum endotoxin in cockerels. Veterinarski Arhiv, 72: 269-276.
Mdegela R, Msoffe P, Waihenya R, Kasanga C, Mtambo M, Minga U & Olsen J. 2002. Comparative Pathogenesis of Experimental Infections with Salmonella gallinarum in Local and Commercial Chickens. Tropical Animal Health and Production, 34: 195–204. DOI: 10. 1023/A:1015226507721
Medical Economics Company. 2001. Prebiotics. In: PDR for Nutritional Supplements (1st Ed.). Physicians' Desk Reference (PDR); Demoines, Iowa/Medical Economics Data Production Company; Montvale, New Jersey, pp. 372-375.
Midilli M, Alp M, Kocabach N, Muglah OH, Turan N, Yilmaz H & Cakir S. 2008. Effects of dietary probiotic and prebiotic supplementation on growth performance and serum IgG concentration of broilers. South African Journal of Animal Science, 38: 21–27. DOI: 10.4314/sajas.v38i1. 4104
Montgomery HAC & Dymock J. 1961. The determination of nitrite in water: colorimetric method of nitric oxide assay. Analyst, 86: 414-416.
Munyaka PM, Echeverry H, Yitbarek A, Camelo-Jaimes G, Sharif S, Guenter W & Rodriguez-Lecompte JC. 2012. Local and systemic innate immunity in broiler chickens supplemented with yeast-derived carbohydrates. Poultry Science, 91: 2164–2172. DOI: 10.3382/ps.2012-02306
Prado-Rebolledo OF, Delgado-Machuca JJ, Macedo-Barragan RJ, Garcia-Márquez LJ, Morales-Barrera JE, Latorre JD & Tellez G. 2017. Evaluation of a selected lactic acid bacteria-based probiotic on Salmonella enterica serovar Enteritidis colonization and intestinal permeability in broiler chickens. Avian Pathology, 46: 90–94. DOI: 10.1080/03079457.2016. 1222808
Rishi P, Mavi SK, Bharrhan S, Shukla G & Tewari R. 2009. Protective efficacy of probiotic alone or in conjunction with a prebiotic in Salmonella-induced liver damage. FEMS Microbiology Ecology, 69: 222–230. DOI: 10.1111/j.1574-6941.2009.00703.x
SAS User’s Guide: Statistics, Version 8.1 Edition, 2000, SAS Institute Inc., Cary, North Carolina. USA.
Satoh K. 1978. Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. Clinical Chimical Acta, 90: 37-43. DOI: 10.1016/0009-8981(78)90081-5
Schrezenmeir J & de Vrese M. 2001. Probiotics, prebiotics, and synbiotics--approaching a definition. The American Journal of Clinical Nutrition, 73 (2 Suppl): 361S-364S. DOI: 10.1093/ajcn/73.2.361s
Shah SN, Kamil SA, Darzi MM, Mir MS & Bhat SA. 2013. Haematological and some biochemical changes in experimental fowl typhoid infection in broiler chickens. Comparative Clinical Pathology, 22: 83–91. DOI: 10.1007/s00580-011-1371-8
Shehata AA, Basiouni S, Elrazek AA, Sultan H, Tarabees R, Elsayed MSAE, Talat S, Moharam I, Said A, Mohsen WA & Krüger M. 2019. Characterization of Salmonella enterica isolated from poultry hatcheries and commercial broiler chickens. Pakistan Veterinary Journal, 39: 515-520. DOI: 10.29261/pakvetj/2019.033
Shehata AA, Herrmann K, Pfalz T, Hafez HM, Schrödl W & Krüger M. 2017. Efficacy of cold fogging and oral herbal extracts on air quality and immune response of broilers. Aerobiologia, 33: 37–47. DOI: 10.1007/s10453-016-9448-0
Tarabees R, Gafar KM, EL-Sayed MS, Shehata AA & Ahmed M. 2019. Effects of dietary supplementation of probiotic mix and prebiotic on growth performance, cecal microbiota composition, and protection against Escherichia coli O78 in broiler chickens. Probiotics and Antimicrobial Proteins, 11: 981–989. DOI: 10. 1007/s12602-018-9459-y
Taylor A, Verhagen J, Blaser K, Akdis M & Akdis CA. 2006. Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: the role of T regulatory cells. Immunology, 117: 433–442. DOI: 10.1111/j. 1365-2567.2006.02321.x
Tellez G, Pixley C, Wolfenden RE, Layton SL & Hargis BM. 2012. Probiotics/direct fed microbials for Salmonella control in poultry. Food Research International, 45: 628–633. DOI: 10.1016/j. foodres.2011.03.047
Waewdee P, Sukon P, Chaveerach P, Surachon P & Soikum C. 2012. Effect of a single dose of Lactobacillus salivarius on prevention of Salmonella enteritidis infection in young broilers. Journal of Animal and Veterinary Advances, 11: 955–961. DOI: 10.3923/javaa.2012.955.961
Withanage GS, Kaiser P, Wigley P, Powers C, Mastroeni P, Brooks H, Barrow PA, Smith A, Maskell D & McConnell I. 2004. Rapid expression of chemokines and proinflammatory cytokines in newly hatched chickens infected with Salmonella enterica serovar Typhimurium. Infection and Immunity, 72: 2152-2159. DOI: 10.1128/IAI.72.4.2152-2159.2004
Xin J, Zeng D, Wang H, Sun N, Zhao Y, Dan Y & Ni X. 2020. Probiotic Lactobacillus johnsonii BS15 Promotes Growth Performance, Intestinal Immunity, and Gut Microbiota in Piglets. Probiotics and Antimicrobial Proteins, 12: 184-193. DOI: 10.1007/s12602-018-9511-y Zhang JL, Xie QM, Ji J, Yang WH, Wu YB, Li C & Bi YZ. 2012. Different combinations of probiotics improve the production performance, egg quality, and immune response of layer hens. Poultry Science, 91: 2755–2760. DOI: 10.3382/ps.2012-02339 | ||
|
آمار تعداد مشاهده مقاله: 1,458 تعداد دریافت فایل اصل مقاله: 1,006 |
||
سامانه مدیریت نشریات علمی. طراحی و پیاده سازی از سیناوب